Research is the driving force behind progress in multiple sclerosis, turning scientific discoveries into meaningful advances in patient care and treatment. This two-hour session will explore how clinical research is integrated into patient-centered MS practice and highlight the contributions of every research team member, including neurologists, coordinators, and program managers, in advancing innovation. Designed for an intermediate to advanced audience, the symposium offers an in-depth look at research operations within a leading MS center. Dr. Mark Freedman will trace the evolution of MS research, from landmark clinical trials to emerging therapeutic approaches, emphasizing the partnership between science and clinical care that drives discovery. Marjorie Bowman, a former study coordinator who helped launch the pivotal BMT for MS trial and is the APN Manager of a large MS Clinic, will provide a perspective on embedding research into routine care. She will share strategies for trial recruitment, maintaining a dynamic patient database, integrating research discussions into therapy planning, interdisciplinary research and managing patients returning from studies. She will show how the clinic supports research and improves patient outcomes. Dawn Carle will conclude with practical guidance on building and sustaining a strong research infrastructure. She will highlight the essential role of study coordinators in conducting feasibilities, engaging physicians, linking patients to trials, and managing a clinical investigations unit that is sustainable and adaptable for diverse studies. Her insights will demonstrate how effective coordination enhances both patient care and research success. Together, the presenters will show how empowering research teams, particularly coordinators, accelerates discovery and strengthens the foundation for future breakthroughs. Level of Information: Intermediate, AdvancedResearch is the driving force behind progress in multiple sclerosis, turning scientific discoveries into meaningful advances in patient care and treatment. This two-hour session will explore how clinical research is integrated into patient-centered MS practice and highlight the contributions of every research team member, including neurologists, coordinators, and program managers, in advancing innovation. Designed for an intermediate to advanced audience, the symposium offers an in-depth look at research operations within a leading MS center. Dr. Mark Freedman will trace the evolution of MS research, from landmark clinical trials to emerging therapeutic approaches, emphasizing the partnership between science and clinical care that drives discovery. Marjorie Bowman, a former study coordinator who helped launch the pivotal BMT for MS trial and is the APN Manager of a large MS Clinic, will provide a perspective on embedding research into routine care. She will share strategies for trial recruitment, maintaining a dynamic patient database, integrating research discussions into therapy planning, interdisciplinary research and managing patients returning from studies. She will show how the clinic supports research and improves patient outcomes. Dawn Carle will conclude with practical guidance on building and sustaining a strong research infrastructure. She will highlight the essential role of study coordinators in conducting feasibilities, engaging physicians, linking patients to trials, and managing a clinical investigations unit that is sustainable and adaptable for diverse studies. Her insights will demonstrate how effective coordination enhances both patient care and research success. Together, the presenters will show how empowering research teams, particularly coordinators, accelerates discovery and strengthens the foundation for future breakthroughs. Level of Information: Intermediate, Advanced