Journal Club: The Dilemma of When to Stop Disease-Modifying Therapy in Multiple Sclerosis

Release Date: August 24, 2020

Valid for Credit Through: August 31, 2021


Advanced Perspectives in MS: A Virtual Journal Club Series for the Multiple Sclerosis Clinician


The Dilemma of When to Stop Disease-Modifying Therapy in Multiple Sclerosis


This activity has been designed to meet the educational needs of physicians, PAs, nursing professionals, pharmacists and other members of the healthcare team involved in the management of patients with MS.


Upon completing this activity, participants should be better able to:

Identify the latest research and clinical information available in the literature with regard to MS diagnosis, treatment, and monitoring.


John F. Kramer, PA-C
STMP Neurology
Nashville, TN

Bryan D. Walker, MHS, PA-C, MSCS
Duke University Medical Center
Durham, NC


This activity is supported by educational grants from Celgene Corporation, EMD Serono, Genentech, and Mallinckrodt Pharmaceuticals.


In support of improving patient care, the Consortium of Multiple Sclerosis Centers (CMSC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. The CMSC has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria.

The Consortium of Multiple Sclerosis Centers designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The Consortium of Multiple Sclerosis Centers designates this enduring material for 1.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.

The Consortium of Multiple Sclerosis Centers designates this enduring material for 1.0 contact hours of continuing education (1.0 in the area of pharmacology) for nurses.

This knowledge-based activity (UAN # JA4008165-0000-20-045-H01-P) qualifies for 1.0 contact hour (0.1 CEUs) of continuing pharmacy education credit.

All other healthcare professionals completing this activity will be issued a certificate of participation.


In accordance with the ACCME Standards for Commercial Support, CMSC requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. CMSC resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all their educational programs. Furthermore, CMSC seeks to verify that all scientific research referred to, reported, or used in a CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. CMSC is committed to providing learners with high-quality CE activities that promote improvements in health care and not those of a commercial interest.

The program faculty reported the following relevant financial relationships that they have with commercial interests:

John F. Kramer, PA-C (Planner) has disclosed the following relevant financial relationships: Consulting Fees: Biogen, EMD Serono, and Novartis Pharmaceuticals; Speakers Bureau: Alexion, Biogen, EMD Serono, and Genentech.

Bryan D. Walker, MHS, PA-C, MSCS (Planner) has disclosed the following relevant financial relationships: Consulting Fees: Biogen, EMD Serono, Novartis, and Sanofi-Genzyme; Speakers Bureau: Biogen.

The planners, reviewers, editors, staff, or other members at CMSC who are in a position to control content have declared that they have no relevant financial relationships.

CMSC requires faculty to disclose to the attendees when products or procedures being discussed are off-label, unlabeled, experimental, and/or investigational (not FDA approved); and any limitations on the information that is presented, such as data that are preliminary or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of US Food and Drug Administration approved labeling. This information is intended solely for continuing education and is not intended to promote off-label use of these medications. If you have questions, contact the medical affairs department of the manufacturer for the most recent prescribing information.


CMSC presents this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. CMSC and the commercial supporters assume no liability for the information herein.


To successfully complete this activity, the participant must review the accreditation information, including learning objectives and faculty disclosures, view the webinar, and complete the evaluation.

  1. To complete the evaluation and claim credit, please click on the To Claim Credit button below or go to:
  2. Log in with your user name and password*, or create a new account.
  3. Select the Enduring Materials tab, then select this activity from the listing and follow the instructions to complete the activity and receive your credit.

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There is no fee to participate in this activity.


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If you have any questions about this activity, please contact the CMSC at [email protected] or 201-487-1050, ext. 102.

About Me

The Continuing Medical Education Program is an integral part of the organization’s overall mission which aims to improve learners’ competence and performance‐in‐practice and ultimately improve patient outcomes.

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