Multiple Sclerosis Management in Primary Care

Release Date: October 29, 2021

Expiration Date: October 28, 2022

Program Description

Multiple sclerosis (MS) impacts nearly 1 million adults in the United States—often beginning in the prime of a patient’s life, between 20 and 50 years of age. Though a lifelong condition, with early diagnosis, referral to a neurology specialist, and initiation of treatment, patients with MS can experience slowed disease progression and minimized relapses. However, as most patients will present to a primary care provider prior to being diagnosed and throughout their disease, clinicians in primary care must be able to recognize clinical signs of MS; initiate a diagnostic workup; and counsel patients through relapses, pseudorelapses, and medication adherence. In this activity, an experienced neurology PA offers insights on how primary care providers can best support and care for their patients with MS—covering early recognition through strategies for long-term management, including during the COVID-19 pandemic.


eNewsletter with interactive benchmarking and video commentary

Learning Objectives

After completing this activity, participants should be better able to:

  • Initiate an appropriate diagnostic evaluation in patients with signs and symptoms suggestive of MS
  • Distinguish the signs and symptoms of relapse versus pseudorelapse in MS
  • Implement guideline-recommended strategies to address medication adherence, potential treatment-related toxicities, and long-term management of MS, including management during COVID-19

Target Audience

NPs and PAs


Bryan D. Walker, MHS, PA-C
Physician Assistant
Division of Multiple Sclerosis and Neuroimmunology
Duke University
Durham, North Carolina

Joint Accreditation Statement

In support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

ANCC Credit Designation

NP course advisor: June Halper, MSN, APN-C, Consortium of Multiple Sclerosis Centers, Hackensack, New Jersey
Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit

AAPA Credit Designation

Practicing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until October 28, 2022. PAs should only claim credit commensurate with the extent of their participation.

IPCE Credit Designation

IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.


This program was cosupported by educational grants from AbbVie Inc.; Astellas; Genentech, a member of the Roche Group; Novo Nordisk; Regeneron; and Urovant Sciences, Inc.

This activity is supported by an educational grant from Genentech.

Practicing Clinicians Exchange gratefully acknowledges the Consortium of Multiple Sclerosis Centers (CMSC) for their contributions as an educational partner for this program.


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.


All faculty and planners participating in continuing education activities sponsored by Practicing Clinicians Exchange (PCE) are required to disclose to the audience all financial relationships with ineligible companies. All relevant conflicts of interest are thoroughly vetted and mitigated according to PCE policy. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and Planning Committee have been advised that this activity must be free from commercial bias and based upon all available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.

Ms Halper: consulting fees: EMD Serono.

Mr Walker: consulting fees: Biogen, EMD Serono, Novartis, Sanofi-Genzyme.

None of the members of the Planning Committee or PCE staff have any relevant relationships to disclose, except Ms Halper as noted above.

How to Receive Credit

Participants wishing to earn CE/CME credit must:

  1. Review the content in its entirety
  2. Relate the content material to the learning objectives
  3. Complete the post-test and evaluation formSuccessful completion of the post-test is required to earn CE/CME credit.

Successful completion is defined as a cumulative score of at least 67%.

The estimated time to complete this activity is 1.00 hour.

Release date: October 29, 2021
Expiration date: October 28, 2022

Contact Information

For Practicing Clinicians Exchange general information, contact [email protected].

About Me

The Continuing Medical Education Program is an integral part of the organization’s overall mission which aims to improve learners’ competence and performance‐in‐practice and ultimately improve patient outcomes.

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