The Role of B Cells in Progressive MS and the Long-term Effects of B Cell Depletion

This activity is jointly provided by The Consortium of Multiple Sclerosis Centers
and The France Foundation.

Release Date: March 31, 2023
Expiration Date: March 30, 2024

This educational activity is intended for neurologists, multiple sclerosis (MS) subspecialists, primary care clinicians, advanced practice clinicians, nurses, pharmacists, and other members of the comprehensive MS care team.


With a focus on progressive disease, hear from leading MS expert Joseph Berger, MD on B-cell related therapies in MS and associated short- and long-term consequences.


Upon completion of this course, the learners should be able to:

  • Explain the most recent advances in the understanding of MS immunology, based on the latest science, in order to initiate and sustain appropriate treatments

Joseph R. Berger, MD
Professor Neurology
Associate Director of the MS Division
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania


Joseph R. Berger, MD
Professor Neurology
Associate Director of the MS Division
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania

Margaret Das, PhD
Senior Medical Writer
The France Foundation
Old Lyme, Connecticut


In support of improving patient care, this activity has been planned and implemented by the Consortium of Multiple Sclerosis Centers (CMSC) and The France Foundation. The CMSC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


The Consortium of Multiple Sclerosis Centers designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


The Consortium of Multiple Sclerosis Centers designates this activity for 0.50 contact hours.

All other healthcare professionals completing this course will be issued a statement of participation.


In accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education, The Consortium of Multiple Sclerosis Centers (CMSC) and The France Foundation (TFF) require that individuals in a position to control the content of an educational activity CMSC and TFF resolve all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all their educational programs.

Furthermore, CMSC and TFF seek to verify that all scientific research referred to, reported, or used in a CME/CE activity conforms to the generally accepted standards of experimental design, data collection, and analysis. CMSC and TFF are committed to providing learners with high-quality CME/CE activities that promote improvements in health care and not those of a commercial interest.

Planning committee members, faculty, reviewers, and activity staff have disclosed the following relevant financial relationships. All relevant financial relationships listed have been mitigated.


CMSC and TFF require CME faculty (speakers) to disclose when products or procedures being discussed are off label, unlabeled, experimental and/or investigational, and any limitations on the information that is presented, such as data that are preliminary, or that represent ongoing research, interim analyses, and/or unsupported opinion. Faculty in this activity may discuss information about pharmaceutical agents that is outside of US Food and Drug Administration approved labeling. This information is intended solely for continuing medical education and is not intended to promote off-label use of these medications. CMSC and TFF do not recommend the use of any agent outside of the labeled indications. If you have questions, contact the Medical Affairs Department of the manufacturer for the most recent prescribing information.


This activity is supported by an educational grant from Novartis.


The Consortium of Multiple Sclerosis Centers and The France Foundation present this information for educational purposes only. The content is provided solely by faculty who have been selected because of recognized expertise in their field. Participants have the professional responsibility to ensure that products are prescribed and used appropriately on the basis of their own clinical judgment and accepted standards of care. The Consortium of Multiple Sclerosis Centers, The France Foundation, and the commercial supporter(s) assume no liability for the information herein.


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  • The materials are to be used solely for personal, noncommercial, informational, and educational purposes. The materials are not to be modified. They are to be distributed in the format provided with the source clearly identified. The copyright information or other proprietary notices may not be removed, changed, or altered.
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Additional information regarding The France Foundation’s Privacy Policy can be viewed at


If you have questions about this CME activity, please contact The France Foundation at 860-434-1650 or [email protected].


There are no fees for participating and receiving credit for this activity. Successful completion is achieved by reviewing the CE information, completing the pre-test, completing the activity, and completing the post-test and evaluation form. A score of at least 75% on the posttest is required to successfully complete this activity. The participant may take the test until successfully passed.

Credit Fulfillment
If you are requesting AMA credits, ANCC credits, or a certificate of participation your certificate will be available for download

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About Me

The Continuing Medical Education Program is an integral part of the organization’s overall mission which aims to improve learners’ competence and performance‐in‐practice and ultimately improve patient outcomes.

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