Carolina Tramontini, MD1, Juan Mora, MD1, Jorge Suárez, MD1 and Carlos Navas, MD2, (1)Diagnostic Imaging, Fundación Universitaria Sanitas, Bogota, Colombia, (2)FUNDACION UNIVERSITARIA SANITAS, BOGOTA, Colombia

Carolina Tramontini, MD1, Juan Mora, MD1 and Carlos Navas, MD2, (1)Diagnostic Imaging, Fundación Universitaria Sanitas, Bogota, Colombia, (2)FUNDACION UNIVERSITARIA SANITAS, BOGOTA, Colombia

Carolina Tramontini, MD1, Juan Mora, MD1 and Carlos Navas, MD2, (1)Diagnostic Imaging, Fundación Universitaria Sanitas, Bogota, Colombia, (2)FUNDACION UNIVERSITARIA SANITAS, BOGOTA, Colombia

Elizabeth A Hubbard, MSc1, Nathan C Wetter, MD2, Bradley P Sutton, PhD2, Lara A Pilutti, PhD1 and Robert W Motl, PhD1, (1)Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL, (2)Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL

Jeffrey Gluckstein, BS1, Gautam Adusumilli, Undergraduate Student2, Samantha Lancia, MS2, Courtney Dula, MS2, Junqian Xu, PhD3, Joanne M Wagner, PT, PhD4 and Robert T Naismith, MD5, (1)Neurology, Washington University, Saint Louis, MO, (2)Department of Neurology, Division of Neuroimmunology, Washington University School of Medicine in St. Louis, St. Louis, MO, (3)Radiology, Mount Sinai School of Medicine, New York, NY, (4)Department of Physical Therapy and Athletic Training, Saint Louis University, St. Louis, MO, (5)Neurology, Washington University School of Medicine, St Louis, MO

Juan Mora, MD1, Jorge Suárez, MD1, Carolina Tramontini, MD1 and Carlos Navas, MD2, (1)Diagnostic Imaging, Fundación Universitaria Sanitas, Bogota, Colombia, (2)FUNDACION UNIVERSITARIA SANITAS, BOGOTA, Colombia

Juan Mora, MD1, Carolina Tramontini, MD1 and Carlos Navas, MD2, (1)Diagnostic Imaging, Fundación Universitaria Sanitas, Bogota, Colombia, (2)FUNDACION UNIVERSITARIA SANITAS, BOGOTA, Colombia

Mirla Avila, MD, Sasikanth Gorantla, MD, Angel O Claudio, MD and John DeToledo, MD, Neurology, Texas Tech, Lubbock, TX

Mohammad Abdoli, MD1, Santanu Chakraborty, MD, MRCP2, Heather MacLean, MD, FRCPC1 and Mark S Freedman, MD3, (1)Neurology, University of Ottawa, Ottawa, ON, Canada, (2)Neuroradiology, University of Ottawa, Ottawa, ON, Canada, (3)University of Ottawa and the Ottawa Hospital Research Institute, Ottawa, ON, Canada

Olivia M Gutgsell, BS1, Luka Vlahovic, MD1 and Matthew McCoyd, MD2, (1)Loyola University Chicago Stritch School of Medicine, Maywood, IL, (2)Loyola University of Chicago MS Clinic, Maywood, IL

Rahil M Dharia, BSc1,2, Esmaeil Davoodi-Bojd, PhD1, Quan Jing, PhD1, Lian Li, PhD1 and Mirela Cerghet, MD, PhD1, (1)Neurology, Henry Ford Hospital, Detroit, MI, (2)School of Medicine, Wayne State University, Detroit, MI

Allison LaRussa, BA1, Alicia S Chua, M.S.2, Brian C Healy, PhD1, Fiona Stuart, BA1, Kaitlynne Leclaire, BA1, Riley Bove, MD1, Maria K Houtchens, MD1, Sandra Cook, RN1, Tanuja Chitnis, MD3, Howard L Weiner, MD1 and Bonnie I Glanz, PhD4, (1)Neurology, Brigham and Women’s Hospital, Brookline, MA, (2)Partners MS Center, Brigham and Women’s Hospital, Brookline, MA, (3)Massachusetts General Hospital for Children, Boston, MA, (4)Partners Multiple Sclerosis Center, Brigham and Women’s Hospital, Brookline, MA

Amber Salter, PhD, Division of Biostatistics, Washington University in St. Louis, St. Louis, MO, Nina Thomas, MPH, Genentech, Inc, South San Francisco, CA, Gary Cutter, PhD, University of Alabama at Birmingham, Birmingham, AL, Tuula Tyry, PhD, Dignity Health, St. Joseph’s Hospital and Medical Center, Phoenix, AZ and Ruth Ann Marrie, MD, PhD, University of Manitoba, Winnipeg, MB, Canada

Amy Bowen, RN, MA, Multiple Sclerosis Trust, Letchworth, United Kingdom of Great Britain and Northern Ireland

Sibyl Wray, MD1, Barry A Singer, MD2, Brooke Hayward, SM, MBA3 and Choon Cha, MD3, (1)Hope Neurology Multiple Sclerosis Center, Knoxville, TN, (2)The MS Center for Innovations in Care, Missouri Baptist Medical Center, St Louis, MO, (3)EMD Serono, Inc., Rockland, MA

Cynthia B. Guerra, MBA1, Brandy Northcutt, _1, Richard Muser, _1, Michael Russo, _1, Joe McBride, _2 and Adrian L. Rabinowicz, MD1, (1)Acorda Therapeutics, Inc, Ardsley, NY, (2)Studio PMG, Irvine, NY

Donald Barone, DO1, Mark Gudesblatt, MD2, Susan E Bennett, PT, DPT, EdD, NCS, MSCS3, Megan Weigel, DNP, ARNP-C, MSCN4, Amy Perrin Ross, APN, MSN, CNRN, MSCN5, Brooke Hayward, SM, MBA6 and Frederick Munschauer, MD6, (1)Rowan University, Stratford, NJ, (2)South Shore Neurologic Associates, Patchogue, NY, (3)State University of New York at Buffalo, Buffalo, NY, (4)Baptist Neurology Beaches Division, South Jacksonville Beach, FL, (5)Loyola University Chicago, Maywood, IL, (6)EMD Serono, Inc., Rockland, MA

Doug Taylor, BSc1, Nipa Patel, BA2 and Philip Sjostedt, BPharm2, (1)Institute for Evidence Based Medicine, New Hope, PA, (2)The Medicine Group, New Hope, PA

Edward J. Fox, MD, PhD1, John Ko, Pharm.D, MS2, Paul Wicks, PhD3, Yujin Park, PharmD4, Pronabesh DasMahapatra, MD, MPH3, Kathryn Kendall, MBA3, Walter Hong, MD2, Erik Burton, MD2, Kathleen Hawker, MD2, Irina Kosoy, BBA5, Dimitri Liakhovitski, PhD5 and Vivian Herrera, DDS, MIA, MPH2, (1)Central Texas Neurology Consultants, Round Rock, TX, (2)Health Economics & Outcomes Research, Novartis Pharmaceuticals Corporation, East Hanover, NJ, (3)PatientsLikeMe Inc., Cambridge, MA, (4)Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD, (5)North America, Gfk, New York, NY

Fiona Stuart, BA1, Alicia S Chua, M.S.2, Allison LaRussa, BA1, Kaitlynne Leclaire, BA1, Sandra Cook, RN1, Tanuja Chitnis, MD3, Howard L Weiner, MD1, Brian C Healy, PhD4 and Bonnie I Glanz, PhD5, (1)Neurology, Brigham and Women’s Hospital, Brookline, MA, (2)Partners MS Center, Brigham and Women’s Hospital, Brookline, MA, (3)Massachusetts General Hospital for Children, Boston, MA, (4)Biostatistics Center, Massachusetts General Hospital, Boston, MA, (5)Partners Multiple Sclerosis Center, Brigham and Women’s Hospital, Brookline, MA

Gregory D Salinas, PhD1, Brandon Coleman, BS1, Eleana Hardy, BA2, Jeffrey Smith, MS MBA2, Leslie Meltzer, PhD2 and Terrie Livingston, PharmD2, (1)CE Outcomes, LLC, Birmingham, AL, (2)Biogen, Cambridge, MA

Heidi Crayton, MD1, Brian Steingo, MD2, DeRen Huang, MD, PhD3, Xiangyi Meng, PhD4, Lesley Schofield, PhD4, Kristen Johnson, PhD4, Nadia Tenenbaum, MD4 and * on behalf of the PREFERMS investigators, **please delete**5, (1)MS Center of Greater Washington, Vienna, VA, (2)Sunrise Medical Group, Sunrise, FL, (3)Neurology and Neuroscience Associates, Akron, OH, (4)Novartis Pharmaceuticals Corporation, East Hanover, NJ, (5)**please delete**, **please delete**, NJ

Hollie Schmidt, MS1, Robert N. McBurney, PhD1, Deborah Backus, PT, PhD2, Laura Kolaczkowski, BA1, Sara Loud, MSEE, MBA1 and Revere P. Kinkel, MD3, (1)Accelerated Cure Project for MS, Waltham, MA, (2)Multiple Sclerosis Institute, Shepherd Center, Atlanta, GA, (3)University of California San Diego, San Diego, CA

Jacqueline Nicholas, MD, MPH1, John Ko, Pharm.D, MS2, Yujin Park, PharmD3, Prakash Navaratnam, Rph, MPH, PhD4, Howard Friedman, PhD4, Frank Ernst, Pharm.D, MS5, Erik Burton, MD2, Walter Hong, MD2 and Vivian Herrera, DDS, MIA, MPH2, (1)Neuroscience, Ohio Health, Columbus, OH, (2)US Health Economics & Outcomes Research, Novartis Pharmaceuticals Corporation, East Hanover, NJ, (3)Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD, (4)DataMed Solutions LLC., Hilliard, OH, (5)Health Economics & Outcomes Research, Indegene TTM, Kennesaw, GA

John Foley, MD, Tamara Hoyt, MS, Cortnee Roman, NP, Angelene Christensen, BS and Ryan Metzger, PhD, Rocky Mountain MS Research Group, Salt Lake City, UT

Joss Cohen, MD candidate1, Katelyn S. Kavak, MS2, Caila B Vaughn, MPH2,3,4, Robert Zivadinov, MD, PhD2,5, Jessica F Robb, MD2,6, Burk Jubelt, MD2,7, Lore Garten, MD2,8, Ilya Kister, MD2,9, Lauren Krupp, MD2,9, Malcolm Gottesman, MD2,10, Barbara E. Teter, PhD, MPH4 and Bianca Weinstock-Guttman, MD2,3,4, (1)Neurology, University at Buffalo Jacobs School of Medicine, Buffalo, NY, (2)New York State Multiple Sclerosis Consortium, Buffalo, NY, (3)Jacobs MS Center of Treatment and Research, Buffalo, NY, (4)Department of Neurology, University at Buffalo, Buffalo, NY, (5)Department of Neurology, State University of New York at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, NY, (6)University of Rochester Medical Center, Rochester, NY, (7)SUNY Upstate Medical University, Syracuse, NY, (8)MS Center of Northeastern New York, Latham, NY, (9)NYU Langone Medical Center, New York, NY, (10)Winthrop Comprehensive MS Care Center, Mineola, NY

Kelsey Zorn, BA1, Katherine J Kim, MPH2, Louis S. Matza, PHD2, Glenn Phillips, PhD3, Kitty S. Chan, PHD4, Sandra D. Cassard, ScD5, Katherine C Smith, PhD1 and Ellen Mowry, MD, MCR5, (1)Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, (2)Evidera, Bethesda, MD, (3)Biogen, Cambridge, MA, (4)Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, (5)Neurology, Johns Hopkins School of Medicine, Baltimore, MD

Kiren Kresa-Reahl, MD1, Pavle Repovic, MD, PhD2, Derrick S Robertson, MD3, Macaulay Okwuokenye, DrPH4, Leslie Meltzer, PhD4 and Jason Mendoza, PhD4, (1)Providence Multiple Sclerosis Center, Portland, OR, (2)Multiple Sclerosis Center, Swedish Neuroscience Institute, Seattle, WA, (3)Neurology, University of South Florida, Tampa, FL, (4)Biogen, Cambridge, MA

Andrew J Solomon, MD1, Haiyan Qu, PhD, MHSA2, Vicky Springmann, MSc3, Carolina Ionete, MD, PhD4, Enrique Alvarez, MD5, Lori Pbert, PhD4, Carolyn Griffin, RN6, Brenda Tierman, RN7, Ashli Hopson, BA7, Christen Kutz, PA, PhD8, Idanis Idanis Berriosmorales, MD4, Glenn Phillips, PhD9 and Nananda F Col, MD, MPH, MPP, FACP7, (1)Neurological Sciences, University of Vermont College of Medicine, Burlington, VT, (2)Minority Health & Health Disparities Research Center; Health Services Administration, University of Alabama, Birmingham, Birmingham, AL, (3)Public Health Ontario, Toronto, ON, Canada, (4)University of Massachusetts Memorial Medical Center, Worcester, MA, (5)Neurology, University of Colorado, Aurora, CO, (6)Department of Neurology, University of Massachusetts Medical School, Worcester, MA, (7)Shared Decision Making Resources, Georgetown, ME, (8)Colorado Springs Neurological Associates, Colorado Springs, CO, (9)Biogen Idec Inc., Weston, MA, USA, Cambridge, MA

Patricia K Coyle, MD1, Chris LaGanke, MD2, Bhupendra Khatri, MD3, Keith R Edwards, MD4, Steve Cavalier, MD5, Pascal Rufi, MD6, Sandrine Brette, MSc7, Miqun Robinson, MD, PhD8, Matt Mandel, MD5 and Ralf Gold, MD9, (1)Stony Brook University, Stony Brook, NY, (2)North Central Neurology Associates, Cullman, AL, (3)The Regional MS Center, Center for Neurological Disorders, Wheaton Franciscan Health Care, Milwaukee, WI, (4)Multiple Sclerosis Center of Northeastern New York, Latham, NY, (5)Genzyme, a Sanofi company, Cambridge, MA, (6)Genzyme, a Sanofi company, Chilly-Mazarin, France, (7)Lincoln, Boulogne-Billancourt, France, (8)Sanofi, Bridgewater, NJ, (9)St. Josef-Hospital, Ruhr University Bochum, Bochum, Germany

Robert L Knobler, MD, PhD, KIND Clinic, Knobler Institute of Neurologic Disease, Fort Washington, PA

Samantha Domingo, Psy.D.1, Lael A. Stone, M.D.2, Shauna Clement, PA-C2, Nicolas Thompson, M.S.3 and Amy Sullivan, Psy.D.4, (1)The Mellen Center for Multiple SclerosisTreatment and Research, Cleveland Clinic, Cleveland, OH, (2)Mellen Center for Multiple Sclerosis, Cleveland Clinic Foundation, Cleveland, OH, (3)Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, (4)The Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, OH

Wanda Castro-Borrero, MD1, Mariko Kita, MD2, Eva Havrdova, MD, PhD3, Bhupendra Khatri, MD4, Keith R Edwards, MD5, Bruce AC Cree, MD, PhD6, Shulian Shang, PhD1, Glenn Phillips, PhD1 and Ying Liu, PhD1, (1)Biogen, Cambridge, MA, (2)Virginia Mason Multiple Sclerosis Center, Seattle, WA, (3)Department of Neurology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, (4)The Regional MS Center, Center for Neurological Disorders, Wheaton Franciscan Health Care, Milwaukee, WI, (5)Multiple Sclerosis Center of Northeastern New York, Latham, NY, (6)University of California San Francisco, San Francisco, CA

Eduardo R Estades, MD1, Angel Chinea, MD2, Yatzka G Hernandez Silvestrini, MD1, Ivonne Vicente, MD2 and Cristina Rubi, BS2, (1)Research/Clinic, San Juan MS Center, Guaynabo, PR, (2)San Juan Multiple Sclerosis Center, Guaynabo, PR

Ana M Canzonieri, DRA, Mauricio O Bando Sr., Sr, Lucas F.R dos Santos Sr., student and Jean I Francisco, Sr, Research, ABEM . Brazilian Association Multiple Sclerosis, São Paulo, Brazil

Andrea Salmon, BAppSci(Occup Therapy), Services Innovation, Multiple Sclerosis Limited, Melbourne, Australia

Bari Talente, JD, National MS Society, Washington, DC

Caila B Vaughn, MPH1,2,3, Katelyn S. Kavak, MS1,2, Barbara E. Teter, PhD, MPH3, Patricia K Coyle, MD2,4, Keith R Edwards, MD, FAAN2,5, Karen Zakalik, MBA1, Muhammad Nadeem, MD3, Lana Zhovtis Ryerson, MD2,6, Allan Perel, MD2,7, Michael Lenihan, MD2,8, Robert Zivadinov, MD, PhD2,9, Lore Garten, MD2,10, Jessica F Robb, MD2,11, Burk Jubelt, MD2,12, Ilya Kister, MD2,6,13, Lauren Krupp, MD2,6, Malcolm Gottesman, MD2,14, Andrew Goodman, MD2,11 and Bianca Weinstock-Guttman, MD1,2,3, (1)Jacobs MS Center of Treatment and Research, Buffalo, NY, (2)New York State Multiple Sclerosis Consortium, Buffalo, NY, (3)Department of Neurology, University at Buffalo, Buffalo, NY, (4)Department of Neurology, Stony Brook University Medical Center, Stony Brook, NY, (5)Multiple Sclerosis Center of Northeastern New York, Latham, NY, (6)NYU Langone Medical Center, New York, NY, (7)Comprehensive Multiple Sclerosis Center of Staten Island, Staten Island, NY, (8)Adirondack Neurology Associates, Glens Falls, NY, (9)Department of Neurology, State University of New York at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, NY, (10)MS Center of Northeastern New York, Latham, NY, (11)Neurology, University of Rochester, Rochester, NY, (12)SUNY Upstate Medical University, Syracuse, NY, (13)Department of Neurology, New York University Medical Center, New York, NY, (14)Winthrop Comprehensive MS Care Center, Mineola, NY

Aisha Bushra, MD1,2, Caila B Vaughn, MPH1,2,3, Katelyn S. Kavak, MS1,2,3, Katia Noyes, PhD, MPH4, Robert Zivadinov, MD, PhD2,5, Jessica F Robb, MD2,6, Burk Jubelt, MD7, Ilya Kister, MD2,8,9, Lauren Krupp, MD2,9, Malcolm Gottesman, MD2,10, Lore Garten, MD2,11 and Bianca Weinstock-Guttman, MD1,2,3, (1)Jacobs MS Center of Treatment and Research, Buffalo, NY, (2)New York State Multiple Sclerosis Consortium, Buffalo, NY, (3)Department of Neurology, University at Buffalo, Buffalo, NY, (4)University of Rochester School of Medicine, Rochester, NY, (5)Department of Neurology, State University of New York at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, NY, (6)University of Rochester Medical Center, Rochester, NY, (7)SUNY Upstate Medical University, Syracuse, NY, (8)Department of Neurology, New York University Medical Center, New York, NY, (9)NYU Langone Medical Center, New York, NY, (10)Winthrop Comprehensive MS Care Center, Mineola, NY, (11)MS Center of Northeastern New York, Latham, NY

Tiffany M. Shih, Ph.D.1, Ning Wu, Ph.D.2, Craig Wakeford, M.A.3 and Darius N. Lakdawalla, Ph.D.1, (1)Precision Health Economics, Los Angeles, CA, (2)Global Health Economics and Outcomes Research, Biogen, Cambridge, MA, (3)Health Economics and Outcomes Research, Biogen, Cambridge, MA